Does Creatine Improve Brain Function? The Answers Revealed

If you enjoy this article, please share it! Sharing helps PSI and helps your friends too!

If you’re looking to stay ahead of the curve, you know that what you put in your body matters. And over the years, more and more people have climbed onto the creatine train. Creatine supplementation has many touted benefits—but one of the most exciting is its potential to improve brain function.

So, does creatine really help with brain function? In this article, we’ll be diving deep into creatine and its effects on the brain. We’ll discuss how it works, how it affects the brain, and what science has revealed about its cognitive benefits thus far. By the end of this article, you’ll be an expert on how creatine affects your brain! Let’s get started!

What Is Creatine and How Does It Affect Brain Function?

If you’ve ever needed an extra mental boost before a big test, or been looking for ways to improve your brain function, you’ve probably heard of creatine. But what is it, exactly?

Creatine is an amino acid that is synthesized by your body from the foods you eat. The primary role of creatine in the body is to create a reservoir of energy for muscle and brain cells. It does this by forming phosphocreatine, which can be quickly accessed when your body needs a burst of energy for tissues or neurons.

Studies have shown that supplemental creatine taken orally can help improve memory and cognitive processes, especially during periods of intense mental focus and stress. Additionally, this supplement has been shown to boost alertness and mood, as well as promoting better sleep quality. In short, creatine can help your brain work more efficiently—essentially giving it an energy boost!

The Science Behind Creatine and Cognitive Performance

It’s true that creatine has been found to improve cognitive performance. Studies have shown that subjects who took creatine for five days performed better on memory tests, had faster reaction times and improved their attention span.

So, why does creatine have these effects? Researchers think it’s because it helps increase the production of energy molecules in the brain. This, in turn, increases the efficiency of nerve impulses, which may explain why some people feel their minds are sharper when taking it. Additionally, there is evidence that suggests creatine can help protect against neurological diseases such as Alzheimer’s.

Finally, several studies have demonstrated that people who take creatine tend to be more alert and more focused when given tasks of cognitive performance. So not only can it boost your concentration levels but it can also help improve other areas of brain functioning as well.


Examining Clinical Studies on Creatine and Brain Function

You may have heard that creatine can improve brain function, but is it true? Well, let’s take a closer look at scientific research.

Clinical Trials

A number of clinical trials have looked at how creatine affects brain function. One meta-analysis of eight double-blind, placebo-controlled studies revealed a significant increase in cognitive performance when compared with the control groups.

Verbal Fluency Tests

In one study, a 20-week trial was conducted on student athletes who took 3g of creatine daily. Subjects were instructed to complete verbal fluency tests at the beginning and end of the study period. The results showed an improvement in working memory and verbal fluency after taking creatine for 20 weeks.

At the end of the day, it appears that scientific evidence supports the use of creatine for improved brain function. While more clinical trials are needed to further explore this topic, current studies have indicated that taking creatine can indeed lead to better thinking ability and improved mental focus.

Benefits of Taking Creatine for Cognitive Function

Creatine could be the extra boost you need for your mental performance. Research suggests that supplementing with creatine can provide various cognitive benefits, such as improved memory, attention, logic tasks and executive function.


Creatine is believed to work by providing a ‘backup’ energy source in the form of phosphocreatine stored in the brain. This energy helps support neuronal activities associated with memory such as neuron signaling and growth. Studies have found that participants who took creatine supplements had improved visual and verbal memory when compared to those given a placebo.

Attention & Logic Tasks

Research has found that supplementing with creatine can improve attention spans, focus and speed of processing. Moreover, participants taking creatine experienced significant improvement in logic task performance when compared to those given a placebo. This suggests that supplementing with creatine might help you maintain your cognitive edge for college exams or important meetings.

From providing an extra energy source for brain cells to helping with attention and logical tasks, the evidence clearly shows that taking creatine could offer significant benefits for cognitive functioning. So if you’re looking for ways to stay sharp mentally, then it may be worth looking into supplementing with creatine – after consulting with your doctor!

Creatine Dosage Considerations

When it comes to taking creatine, the amount you take is important. Taking too much can have some serious side effects—you don’t want to take more than 10g per day. And, it’s advised to take 5g daily as a regular dosage.

So, what about your brain? Well, it seems that for cognitive benefits, 1-5g per day of creatine supplementation should be enough for most adults—and interestingly enough, that’s the same dose generally recommended for muscle performance.

You don’t need to go overboard with your creatine intake; the most effective way to get results is to stick with the recommended dosage and observe how it affects your body over time and be mindful of any changes or side effects that might arise due to taking too much or too little.


What the Research Says About Long-Term Use of Creatine

Now that you know a bit more about creatine and brain function in the short-term, let’s move onto what the research has to say about the long-term use of creatine. Well, it turns out that the effects of creatine on your brain don’t necessarily stop after you stop taking it.

Recent Findings

In recent clinical research, scientists have found that long-term use of creatine can have beneficial impacts on areas of your brain associated with learning, memory, and decision-making abilities. In one study of rats who were given a daily dose of creatine for three weeks, it was found that they had improved performance on tests that tested memory and problem solving.

Also, Interestingly enough, researchers also noted that some of these cognitive benefits were still observed even after the rats had stopped taking creatine for three weeks. It’s worth noting here too that these findings were replicated in similar studies conducted on humans as well.

Creatine Monohydrate vs Creatine Ethyl Ester (CEE)

When it comes to long-term use of creatine and brain health there’s still much to be researched. But so far we can see from clinical and animal studies that regular consumption of creatine monohydrate—but not CEE—may help improve cognitive function over time.

Alternative Approaches to Cognitive Enhancement

Creatine isn’t your only choice when it comes to cognitive enhancement. There are other alternative approaches you can take if you want to improve your brain function.


We’ve all heard the phrase “healthy body, healthy mind” and it really does apply here. A consistent exercise routine helps to increase brain function, improving the speed of mental processing and boosting the production of neurochemicals like serotonin and dopamine.

Healthy Diet

It’s not just your physical health that benefits from a healthy diet, but also your mental health. Eating foods high in omega 3 fatty acids is great for improving brain function as well as promoting emotional wellbeing.

Mental Stimulation

Sometimes something as simple as challenging yourself with puzzles or playing games can help to stimulate your mind and create better cognitive functioning. It’s easier than ever with apps that test memory, problem-solving skills and more on a daily basis!

These are all manageable steps that you can take to help improve your brain function without having to resort to taking any kind of supplements or medications. Whether you choose one or all of these options is up to you, just make sure to do what works best for you and fits into your lifestyle!


The science is still out on how creatine influences brain function, but one thing is for sure—it has the potential to be a powerful nootropic for those looking for a cognitive boost. From improved cognitive functioning to enhanced athletic performance, creatine can provide substantial benefits for anyone looking for an edge in their performance.

Ultimately, the decision to use creatine as a supplement should be based on individual needs, lifestyle, and goals. If you’re looking for improved cognitive performance and overall enhanced physical performance, then creatine could be the answer. However, due to the lack of conclusive evidence, it’s best to speak with your doctor before starting any type of supplementation program.

If you are looking for a creatine supplement, get micronized creatine monohydrate. It’s cheap, mixes well, and works just as well as all the fancy creatine options. This is the brand I use.

Links to the studies that we used to write this article: [1] [2] [3] [4] [5]

Time to go Pump Some Iron!

If you enjoy this article, please share it! Sharing helps PSI and helps your friends too!


Hey, I'm Brian, the creator of I've been weightlifting / bodybuilding for 20 years and now I'm ready to share some knowledge. Check out my About Me page to hear my story.

Recent Articles